Settings of a novel electrosurgical generator to enable efficient and safe submucosal endoscopic procedures

Introduction: A novel electrosurgical generator unit (ESU), ConMed Beamer, was recently introduced to facilitate endoscopic submucosal dissection (ESD) by employing Automatic Cutting Effect (ACE) technology. Its use in endoscopy has yet be investigated. Background and study aims: The aim of this evaluate the feasibility safety performing ESD per-oral myotomy (POEM) using settings generated with Beamer ESU. Patients methods: Single-center prospective 59 consecutive patients undergoing ESD/POEM at a tertiary referral center. ESU were initially testing live animal models prior first in-human study. primary outcome technical success. Secondary outcomes procedure times, rate en bloc/R0 resection, adverse events. Results: 44 (50 polyps) 15 underwent POEM, respectively. En bloc R0 curative resection rates 90%, 77.1%, 70.8%, Mean maximal length lesion 3.07 cm +/- 1.43 an average speed 14.2 cm2/hour 11.1. Technical success achieved 100% POEM patients. time (minutes) complete 50.1 min 12.4. Two major events occurred amongst all (3.4%). All intraprocedural bleeding controlled Conclusion: from proven safe effective cohort who procedures. This can added armamentarium capable generators.